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P31. NOSAS SCORE: WHAT ROLE IN SCREENING PATIENTS

               WITH SEVERE OBSTRUCTIVE SLEEP APNEA?


               SARA.TRIMECH,  EMNA.  BEN  JEMIA,  HEND.  OUERTANI,  SIWAR.REJEB,  HAIFA.  ZAIBI,
               JIHEN. BEN AMAR

               PNEUMOLOGY DEPARTMENT OF CHARLES NICOLLE HOSPITAL. TUNIS EL MANAR UNIVERSITY,
               TUNIS MEDICAL FACULTY, TUNISIA



               Introduction  :  Obstructive sleep  apnea  (OSA) is a prevalent sleep disorder
               characterized  by  repeated  upper  airway  obstruction  during  sleep,  leading  to
               significant  health  risks  if  untreated.  Early  screening  is  essential  for  a  better
               management. Many scores have been validated as useful tools to identify patients
               at      risk     of      OSA        among        which        the      NoSAS        score.
               This study aimed to evaluate the diagnostic performance of the NoSAS
               questionnaire in identifying severe OSA among patients with a confirmed OSA.

               Methods : A cross-sectional study was conducted from January 2023 to June 2024,
               targeting  patients with  a  confirmed  sleep  disorder  in  Charles  Nicolle  University
               Hospital  of  Tunis.  All  patients  included  were  required  to  fulfill  the  NoSAS
               questionnaire. According to the American Academy of Sleep Medicine (AASM) the
               diagnosis and severity of OSA were classified based on the AHI. We divided patients
               into two groups: G1 with severe OSA and G2 with mild to moderate OSA. NoSAS
               score consists of a total of six items comprises neck circumference˃  40 cm
               (4points), BMI between 25-30kg/m2 (3 points), BMI ˃30kg/m2 (5points), snoring

               (2points), age˃55  years (4points) and male sex  (2points).  A NoSAS score  ≥8 is
               suggestive of being at high risk for OSA.

               Results : A total of 172 patients diagnosed with OSA a mean age at 57.4±13 years
               were enrolled. OSA severity was classified as mild in 63 patients (36.6%), moderate
               in 45 (26.2%), and severe in 64 patients (37.2%). NoSAS score was significantly higher
               in patients with severe OSA (G1: 11.4 ± 2.7 vs G2: 10 ± 2.8; p= 0.001). NoSAS score
               demonstrated a high discriminative value, with area under the curve (AUC) of 0.64
               CI [0.56-0.73].  The  sensitivity  (Se)  and  specificity  (Sp)  of  NoSAS  score  were
               respectively, Se=34.8%, Sp=85.6%with a cut-off value of 12.

               Conclusion : NoSAS score had shown its efficacy in detecting rapidly patients with
               severe OSA leading to an early management and lesser complications in the short
               and long term. However, updated versions incorporating emerging data may get rid
               of the limitations and improve the effectiveness.











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